Princess Anne Manor and Gardens is located in the western area of Toronto that was formerly the City of Etobicoke. Its boundaries are Eglinton Avenue to the north, Martin Grove to the west, Islington to the east, and Rathburn Road to the south. The southeastern part of this area is the separate neighbourhood of Thorncrest Village.

The neighbourhood is divided into two areas. The portion east of Kipling Road is known as Princess Anne Manor while the portion west of Kipling is Princess Margaret Gardens. They are named after The Princess Anne and The Princess Margaret, members of the British Royal family.

Princess Anne Manor and Princess Gardens were the last subdivisions to be developed by Home Smith and Company, whose earlier developments included the building of neighbourhoods such as The Kingsway, Baby Point, Old Mill, and Humber Valley Village. Home Smith and Company also built the Brule Gardens subdivision in Swansea, and the Foxwell subdivision in Lambton. 

This is a post-war developed residential area. Its main street is The Kingsway that runs through the centre of this sprawling neighbourhood. Eglinton Avenue, a four-lane arterial road runs east-west along the north of the neighbourhood. Residential subdivisions back onto Eglinton along this stretch. North-south are Martin Grove, Kipling and Islington Avenues, all four-lane arterial roads with detached homes on both sides. The density of the housing is very low, and road patterns are generally curved roads leading into cul-de-sacs to reduce traffic.

Ranch style bungalows and split-level homes on expansive lots are the most typical homes styles in this area, although in-fill building of large two-storey homes has become popular.

Largely built along an extension of the street 'The Kingsway' north of Dundas St, the area developed in a radically different manner than 'The Kingsway' neighbourhood to the south after the northern extension of the Kingsway was cut off from the south with the construction of a highway-style interchange at Dundas and Royal York. Like 'the Kingsway' neighbourhood to the south, many streets in Princess Gardens carry 'royal' names: The Kingsway, Prince George DrIve, Princess Margaret Blvd, Princess Anne Crescent.